The Global Health Policy Center leads CSIS’s research bridging foreign policy and public health communities.

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Photo: PHILL MAGAKOE/AFP via Getty Images

Photo: PHILL MAGAKOE/AFP via Getty Images

PEPFAR’s Golden Era Is Over. It Urgently Needs a Five-Year Transition Plan

There is no path back to PEPFAR’s old model, but with political will and skilled leadership, it is possible to navigate PEPFAR’s reduced capabilities and mission, manage current shocks, ensure an orderly handoff, and achieve an accelerated, five-year transition plan.

Critical Questions by Jirair Ratevosian, J. Stephen Morrison, and Katherine E. Bliss — May 16, 2025

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Katherine E. Bliss
Senior Fellow and Director, Immunizations and Health Systems Resilience, Global Health Policy Center
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Jon B. Alterman
Deputy Director, Global Food and Water Security Program