Besides geographical proximity, the United States has long been actively engaged in advancing regional political and economic ties with its North, South, and Central American neighbors, as well as with Caribbean nations. Although the United States has enjoyed strong partnerships across the Americas, geopolitical rivals such as China and Russia have expanded their influence in the region in recent years. CSIS research highlights both inter- and intra-regional issues on the United States’ doorstep.

Photo: FRANCESCO SPOTORNO/AFP/Getty Images

Photo: FRANCESCO SPOTORNO/AFP/Getty Images

U.S.-Caribbean Relations: The Cost of Postponing the 2025 Summit of the Americas

Americas Program Senior Associate Georges Fauriol and Mary Speck highlight the growing security challenges facing Caribbean nations, including the regional crises in Haiti and Venezuela, and propose a regional solution to the issues at hand.

Commentary by Georges A. Fauriol and Mary Speck — December 8, 2025

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Romina Bandura

Romina Bandura

Senior Fellow, Project on Prosperity and Development
Matthew P. Funaiole

Matthew P. Funaiole

Vice President, iDeas Lab, Andreas C. Dracopoulos Chair in Innovation and Senior Fellow, China Power Project

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Financing Pandemic Preparedness

In the face of deep cuts to global health security programming, actions are unfolding on several fronts to reform pandemic preparedness and response financing. This session will focus on the question: where do things stand, as 2025 draws to a close? What can we anticipate, looking forward into 2026? 

Event — December 10, 2025

The Last Line of Defense

Are the United States and Venezuela on the Brink of War?

Seth Jones sits down with Juan Cruz, who served in the U.S. Intelligence Community and on the National Security Council as special assistant to the president and senior director for Western Hemisphere affairs, to discuss the U.S. military’s role in the Venezuela crisis and provide an inside look at Maduro’s armed forces.

Podcast Episode by Seth G. Jones and Juan Cruz — December 3, 2025

The Last Line of Defence

Mexico: A Pivotal State on the Global Stage

Mexico straddles between the Global North and Global South, leveraging deep integration with the United States while guarding its sovereignty. This chapter explores how history, inequality, and geopolitics shape Mexico’s quest for strategic autonomy on the global stage.

Brief by Ryan C. Berg, Rubi Bledsoe, and Michael Ferguson — December 2, 2025

Fulcrums of Order: Rising States and the Struggle for the Future

As global power diffuses and multilateralism fractures, a set of rising states increasingly claim the mantle of the “Global South,” reshaping institutions, challenging Western dominance, and forcing the United States to rethink how it engages a rapidly changing world.

Report by Jon B. Alterman and Lily McElwee — December 2, 2025

Executive Summary – Fulcrums of Order

As rising powers reshape the global landscape, the United States must shift from defending the status quo to building pragmatic coalitions, addressing Global South grievances, and engaging hinge states with a clear understanding of their politics.

Brief by Jon B. Alterman — December 2, 2025